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خانه Genetic Advances

Genetic Advances: A Pathway to Sustainable Livestock Management

Genetic Advances: A Pathway to Sustainable Livestock Management

V1:
A Basic Understanding of Genetics in Dairy and Beef Cattle

Along with management and environmental factors, genetics plays a vital role in the biology and productivity of livestock. Genes also influence the economic viability of animal agriculture. There are two main types of genetic traits to consider: qualitative and quantitative. Qualitative traits are either present or absent; for example, a beef animal is either polled or not, making “polled” a qualitative trait. In dairy cows, coat color serves as a qualitative trait, particularly in breeds like Holsteins, where black and white coloring patterns are prominent. These traits are generally unaffected by management or environmental factors.

Quantitative traits, on the other hand, vary along a continuum and are influenced by both genetics and external conditions. In dairy cows, milk production, fat percentage, protein content, and somatic cell counts are important quantitative traits, as they impact both the efficiency of milk production and animal health. In beef cattle, traits such as marbling, tenderness, and growth rate are key quantitative characteristics. These traits often involve multiple genes, which is where genetic testing proves valuable.

Genetic Basics and Testing

Genes are strands of DNA, made up of exons and introns. Exons contain the coding regions for proteins, while introns act as non-coding “spacers.” Both exons and introns consist of nucleotides, and a mutation occurs when a nucleotide is substituted, added, or deleted. Single Nucleotide Polymorphisms (SNPs), small variations in DNA sequence, may impact quantitative traits. While individual SNPs generally explain less than 5% of genetic variability, identifying multiple relevant SNPs allows for a more comprehensive understanding of traits like milk yield or marbling.

Each gene may have different alleles, which are variations in nucleotide sequences. For example, a dairy cow carrying the A-allele in a gene associated with milk fat percentage may express higher fat content in her milk compared to a cow with the B-allele. Alleles pair to form genotypes. A dairy cow with two identical alleles (homozygous) for high milk production genes may outperform a heterozygous animal in terms of milk yield. If multiple nucleotides or gene markers are tested simultaneously, the information is often referred to as a haplotype.

Several genotyping services offer tests for traits like polled status, color, feed efficiency, fertility, and carcass quality, with some tests specifically focused on dairy cows. These genetic evaluations can assist dairy producers in selecting for economically advantageous traits, such as higher milk yield, better feed conversion, and improved resistance to diseases.

Economics of Genetic Testing

While genetic testing holds promise, its economic value is still evolving, and producers face challenges due to high testing costs and limited genetic literacy. However, studies have begun exploring the economic impact of genetic variations. For example, SNPs in the leptin gene are associated with fat metabolism and deposition, impacting not only beef cattle but also influencing milk production in dairy cows.

Research shows that Holstein cows with the TT genotype for a specific SNP in the leptin gene can produce an average of 3.3 pounds more milk per day over a 305-day lactation period compared to those with the CC genotype. Such genetic differences translate into notable production gains and profitability for dairy producers, as increased milk yield and optimal milk composition are economically beneficial. Additionally, TT and CT cows in beef operations have been shown to wean heavier calves, contributing to improved profitability due to increased calf weaning weights and potentially longer productive lives.

The Future of Genetic Marker Selection and Breeding

As the economic valuation of genetic markers advances, selecting the right markers can boost profitability. In dairy cattle, markers affecting milk yield, fat, and protein percentages, along with traits like somatic cell count (an indicator of mastitis resistance), are of particular interest. Holstein breeders, for instance, may prioritize traits that improve overall productivity and health, enabling them to meet the demands of a competitive dairy industry.

For beef producers, economic incentives vary by production phase. Cow-calf producers benefit from selecting for high weaning weights, while stockers and feedlot operators prioritize feed efficiency and growth rate. However, incentives may be misaligned across the supply chain; for instance, beef producers are often paid by carcass weight rather than feed efficiency or tenderness. While tenderness is a highly valued trait for consumers, the beef industry currently lacks a widespread system to reward producers for tenderness markers, which could enhance product demand and profitability.

In the dairy industry, large-scale, vertically integrated markets reward traits directly related to milk production efficiency and quality. However, there is still room to develop reward structures for traits affecting dairy cow longevity, disease resistance, and reproductive efficiency. As these market incentives evolve, dairy producers with advanced genetics in their herds will be well-positioned to meet market demands.

 

V2:

A Comprehensive Look at Genetics in Livestock Production

The biology of an animal is shaped by genetics, management practices, and environmental factors. These elements also influence the economic aspects of livestock production. Broadly, animal traits are categorized as either qualitative or quantitative. Qualitative traits, such as coat color or whether an animal is polled, are generally unaffected by environmental factors and are inherited in a straightforward, binary manner—traits are either present or absent.

Quantitative traits, however, are more complex. These include characteristics like growth rate, milk yield, or feed efficiency, which exist on a spectrum and are influenced by multiple genes alongside environmental conditions. Understanding the genetic foundation of these traits is vital for breeders who aim to improve productivity and efficiency in livestock.

The Role of Genes and Genetic Testing

Genes consist of DNA segments, organized into sequences of nucleotides, some of which directly influence traits. Occasionally, a genetic mutation alters a nucleotide within these sequences, a change known as a Single Nucleotide Polymorphism (SNP). While many SNPs have minimal impact, some significantly contribute to variations in important traits, such as feed efficiency in cattle. Often, examining a combination of multiple SNPs is required to understand and enhance complex traits.

For breeders, genotyping services have become essential tools, enabling the selection of animals based on traits like growth rate, reproduction, and meat quality. As a result, genetic insights are gradually influencing breeding strategies across livestock industries.

Economic Implications of Genetic Testing in Dairy and Beef Production

While the field of livestock genetics has advanced, the economic benefits of genetic testing are still being explored. Studies on specific genes, such as the leptin gene in beef and dairy cattle, illustrate how certain SNPs can influence profitability. For instance, variations in the leptin gene can affect fat deposition, influencing both meat quality in beef cattle and milk production in dairy cows. Research shows that animals with certain genotypes may yield more milk or have higher weaning weights, which can directly impact profitability.

In dairy cattle, for example, studies have shown that Holstein cows with a specific leptin SNP produce more milk during lactation. In beef production, genotypes associated with the leptin gene can result in heavier weaning weights and longer productive lives in certain cattle breeds, adding economic value for cow-calf producers. These genetic advantages can translate to financial gains, although the costs of testing must be weighed against potential returns.

Future Prospects of Genetic Selection in Livestock

The integration of genetic marker information into breeding programs is expected to grow as economic evaluation methods improve. For example, traits like high weaning weights, efficient feed conversion, and marbling are increasingly valued at different stages of the livestock supply chain, though the economic benefits for producers may vary based on their position within the industry. For dairy and beef producers alike, identifying and selectively breeding for traits that align with market demand will be essential in the evolving livestock industry.

As the industry advances, we may see more specialized markets for traits that appeal to consumers, such as meat tenderness or nutritional content. Genetic testing could become a valuable tool for aligning breeding practices with consumer preferences, fostering a more sustainable and profitable livestock sector.